Music

The Moment review – it’s not that easy being green

On June 7 2024 Charli XCX unleashed a monster. Green, mean and only 41:23 minutes long, ​‘brat’ wasn’t just an album – it was an entire summer. And then it was a global phenomenon that dominated pop culture long after the leaves turned golden. During her Coachella performance a full 10 months later Charli floated the idea of brat finally coming to a close, but breaking...

TECH

India’s Sarvam launches Indus AI chat app as competition heats up

Sarvam, an Indian AI startup focused on building models for local languages and users, on Friday launched its Indus chat app for web and mobile users, entering a fast-growing market dominated by global players including OpenAI, Anthropic, and Google. The launch comes as India has become a key battleground for generative AI adoption. Recently, OpenAI CEO Sam Altman said ChatGPT...

TECH

General Catalyst commits $5B to India over five years

General Catalyst, a Silicon Valley-based venture firm with more than $43 billion in assets under management, has announced it plans to invest $5 billion in India over the next five years, sharply expanding its push into the country’s startup ecosystem less than two years after merging with local venture firm Venture Highway. The commitment, unveiled at the India AI Impact...

TECH

OpenAI taps Tata for 100MW AI data center capacity in India, eyes 1GW

OpenAI has partnered with India’s Tata Group to secure 100 megawatts of AI-ready data center capacity in the country, with plans to scale to 1 gigawatt. The move is part of a broader push to deepen the company’s enterprise and infrastructure footprint in one of its fastest-growing markets. OpenAI announced on Thursday that the partnership with the Tata Group is...

Nature

The integrated stress response promotes immune evasion through lipocalin 2

Cell linesThe KP cells used here were established previously66. Atf4 and Lcn2 knockout cell lines were generated by transient transfection of PX458 (Addgene, 48138) expressing guides targeting either Atf4 or Lcn2. The list of sequences and primers is included in Supplementary Table 4. Single GFP-positive clones were selected, and gene of interest (GOI) loss was validated by western blot or ELISA....

Science

Sugary drinks linked to rising anxiety in teens

A new study reports a clear association between high sugar drink intake and anxiety symptoms in teenagers. Researchers from Bournemouth University collaborated on a large review that examined findings from multiple earlier studies exploring the relationship between diet and mental health. By analyzing the combined data, the team looked for patterns that appeared consistently across different groups of young people....

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This reengineered HPV vaccine trains T cells to hunt down cancer

Over the last decade, scientists at Northwestern University have identified a key insight about how vaccines work. The ingredients matter, but the way those ingredients are physically arranged can dramatically influence performance. After validating this concept in multiple studies, the researchers applied it to therapeutic cancer vaccines aimed at HPV-driven tumors. In their latest work, they found that simply adjusting...

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